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tTMB-P3(12.41) Reference Standard

CBP80001-3

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I. Background

Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials.

 

Sample ID

Cat.No.

Background

Assay

Comments

DC198N0161

CBP80001-3N

B lymphoblast, Female

500x WES

Same individual

 

DC198N0160

CBP80001-3T

Ductal breast carcinoma, Female

500x WES

IDT xGenExome Research Panel v1.0捕獲,Target Region 39M, Probe Region 51M,CDS Region 33.52M;
HiSeq X-TEN,af選擇0.02 cut off,再過濾。
DC198N0160 is 100% Tumor sample.

 

 

Cut off =2%

Cut off =3%

Cut off =4%

Cut off =5%

Mutation Number

416

398

386

383

TMB value

12.41

11.87

11.52

11.43 

 

計算數(shù)據(jù)下載:DC198N0160.tmb

 

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理:18240630236/15715191010 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 華北銷售經(jīng)理:18628311252 全國銷售經(jīng)理:13816461235
診斷標準品聯(lián)系方式: 華東銷售經(jīng)理:15000320447 華北銷售經(jīng)理:18628311252 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國銷售經(jīng)理:13816461235

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